منابع مشابه
Vascular gp91 Beyond the Endothelium
present compelling evidence for conventional gp91containing NAD(P)H oxidase in the vascular endothelium and for the functional involvement of gp91 in endothelial cell NAD(P)H oxidase superoxide anion (O2) production and aberrant endothelium-dependent relaxation. Many studies have implicated reactive oxygen species in the impairment of endothelium-dependent vascular responses.2–10 Since their in...
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Ann Saudi Med 2006;26(5):343-345 The vascular endothelium is the largest organ in the body. The vessel wall is 5 times the size of the heart in mass and 6 times the size of a tennis court in area. The vessel wall is an active, integrated organ composed of three separate layers: intima, media and adventitia. Histologically, the endothelial cells are very specialized, metabolically active, polyhe...
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During embryonic development, multilineage HSCs/progenitor cells are derived from specialized endothelial cells, termed hemogenic endothelium, within the yolk sac, placenta, and aorta. Whether hemogenic endothelial cells contribute to blood cell development at other sites of definitive hematopoiesis, such as in the fetal liver and fetal bone marrow, is not known. Also unknown is whether such ce...
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Endothelial cell protein C receptor (EPCR) is a type 1 transmembrane glycoprotein with homology to the major histocompatibility complex (MHC)-class 1/CD1 family of molecules.1 EPCR was isolated and cloned as an endothelial cell-specific, high selectivity and high affinity binding protein for protein C (PC) and activated PC (APC).1 EPCR binds PC on the endothelial surface and presents it to the ...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2004
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.0000125646.08156.4d